Given their underlying strategic approach and matchup dynamics, the predictive model expects the 49ers to run on 44.5% of their plays: the lowest frequency on the slate this week.The forecast calls for 13-mph wind in this game. High wind typically means reduced pass volume (and increased run volume) and worse passing effectiveness.The predictive model expects Brock Purdy to notch 4.2 carries in this contest, on balance: the 10th-most out of all quarterbacks.The Bills defensive tackles profile as the 9th-worst collection of DTs in the league this year with their run defense.
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