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This week's spread suggests a passing game script for the Colts, who are -6-point underdogs.The passing offenses of both teams (including both volume and effectiveness) figure to benefit from the calm "weather" conditions (meaning zero wind) inside this dome, while rush volume may slide.Opposing QBs have averaged 35.9 pass attempts per game against the San Francisco 49ers defense this year: 10th-most in football.The Indianapolis Colts offensive line ranks as the best in the NFL this year in protecting the passer, which has a positive impact on all pass attack stats across the board.This year, the porous San Francisco 49ers defense has yielded a whopping 72.6% Adjusted Completion Rate to opposing QBs: the 10th-biggest rate in football.
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