The Titans will be forced to utilize backup quarterback Mason Rudolph in this contest, which generally means fewer pass attempts and more rushes.The Titans are a big 9.5-point underdog in this game, likely creating an extreme passing game script.Opposing offenses have averaged 30.7 pass attempts per game against the Bills defense this year: 10th-fewest in football.The projections expect DeAndre Hopkins to be a more integral piece of his team's pass game in this contest (21.5% projected Target Share) than he has been this year (15.4% in games he has played).DeAndre Hopkins's 67.6% Adjusted Completion Rate this year shows a noteable progression in his receiving talent over last year's 56.6% rate.
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