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The San Francisco 49ers have called the 8th-most plays in the league this year, averaging a massive 59.4 plays per game.This game will be played in a dome—which means zero wind, higher pass volume, higher TD potential, and increased passing effectiveness.The Colts defense has been a notorious pass funnel this year, inducing opposing QBs to attempt the 2nd-most passes in the league (38.9 per game) this year.Christian McCaffrey has been used more as a potential target this season (81.2% Route Participation Rate in games he has played) than he did last season (68.1%).In this week's game, Christian McCaffrey is projected by our trusted projection set to position himself in the 100th percentile when it comes to running backs with 7.2 targets.
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