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With a 12.5-point advantage, the 49ers are a huge favorite in this week's game, suggesting much more of a focus on running than their typical approach.Based on their underlying propensities and matchup dynamics, the predictive model expects the San Francisco 49ers to run on 48.0% of their downs: the 6th-highest frequency among all teams this week.This year, the imposing Tennessee Titans run defense has surrendered a measly 4.97 adjusted yards-per-carry to the opposing ground game: the 26th-smallest rate in the league.
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