Learn About D-Backs vs Cardinals Picks and Betting Trends – Monday June 22, 2026

Arizona Diamondbacks logo

Arizona Diamondbacks

@
St. Louis Cardinals logo

St. Louis Cardinals

+130O/U: 8.5
(-110/-110)
-150

Arizona Diamondbacks Insights

  • Adrian Del Castillo – Over/Under 1.5 Total Bases (+215/-290)
    Extreme groundball hitters like Adrian Del Castillo usually hit better against extreme flyball pitchers like Andre Pallante.
    Explain: This mostly has to do with the way the hitter’s swing plane interacts with the pitch trajectory, and it can create boosted performance across all categories and hidden value few are considering.
  • Arizona Diamondbacks – 2H Moneyline
    The Arizona Diamondbacks bullpen grades out as the 10th-best in Major League Baseball, via the leading projection system (THE BAT).
    Explain: Most bettors only consider the starting pitcher, but a strong bullpen sneakily creates a tougher matchup for the opposing offense and suppresses a game’s runs.

St. Louis Cardinals Insights

  • Andre Pallante – Over/Under 17.5 Pitching Outs (-125/-105)
    Andre Pallante is projected to record an average of 17 outs in today’s matchup, according to the leading projection system (THE BAT X).
    Explain: THE BAT X is a highly sophisticated projection system that accounts for a multitude of factors like ballpark, weather, umpire, defense, and more.
  • Lars Nootbaar – Over/Under 1.5 Total Bases (+140/-185)
    Lars Nootbaar will have the handedness advantage over Merrill Kelly in today’s game.
    Explain: Right-handed hitters perform better against left-handed pitchers (and visa-versa). This can have a huge impact on whether a hitter will perform well or struggle on any given day.
  • Lars Nootbaar – Over/Under 1.5 Total Bases (+140/-185)
    Lars Nootbaar hits a lot of his flyballs to center field (40.4% — 99th percentile) and will have a big advantage facing the game’s 7th-shallowest CF fences in today’s game.
    Explain: This player’s skill set matches up particularly well with the park he’s in today, which may lead to better-than-usual performance.

Betting Trends

  • St. Louis Cardinals – Over/Under 2.5 1st Five Innings (F5) Team Total (-110/-120)
    The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 11 of their last 14 games (+8.30 Units / 50% ROI)
  • Over/Under 8.5 Game Total (-110/-110)
    The Arizona Diamondbacks have hit the Game Total Under in 25 of their last 40 games (+10.90 Units / 25% ROI)
  • Alec Burleson – Over/Under 0.5 Runs (+100/-130)
    Alec Burleson has hit the Runs Under in 15 of his last 20 games at home (+7.45 Units / 23% ROI)