Giants vs Angels Betting Guide and Expert Picks April 19th, 2025

San Francisco Giants

@

Los Angeles Angels

The Los Angeles Angels will host the San Francisco Giants on April 19, 2025, in what promises to be an intriguing interleague matchup. Both teams come into this game with contrasting recent performances; the Angels secured a shutout victory against the Giants just yesterday, winning 2-0, while the Giants look to bounce back after a disappointing loss.

Currently, the Angels sit at 10-9, showing signs of an above-average season, but they face a tough challenge against the Giants, who boast a 13-7 record and are having a great start to their campaign. The Angels’ offense ranks 18th in MLB, while the Giants’ bats are slightly better at 14th, making this a battle of teams that have yet to find their offensive rhythm.

On the mound, the Angels are projected to start Kyle Hendricks, who has struggled this season with a 0-1 record and a 4.20 ERA. His last outing was particularly rough, allowing 5 earned runs in just 4 innings pitched. Hendricks’ projections suggest he may allow 2.9 earned runs today, which could be problematic against a Giants lineup that ranks 4th in strikeouts. On the other hand, Landen Roupp is set to take the hill for San Francisco. Despite a 1-1 record and a higher ERA of 4.80, projections indicate he could allow only 2.2 earned runs, presenting a favorable matchup for the Giants.

With the Giants’ bullpen rated as the 2nd best in MLB and the Angels’ offense struggling to produce consistently, this game could tilt in favor of the visiting Giants. The current odds reflect this, with the Giants favored at -150 and an implied team total of 4.60 runs. In contrast, the Angels, listed as underdogs at +125, have an average implied total of 3.90 runs. With the stakes high, the Giants will aim to leverage their pitching advantage and rebound from yesterday’s loss.

San Francisco Giants Insights

• Landen Roupp – Over/Under 6.5 Strikeouts (+100/-130)
  With 7 bats who share his handedness in the opposing team’s projected batting order, Landen Roupp ought to benefit from having the platoon advantage in most plate appearances in today’s matchup.
  Explain: Right-handed pitchers perform better against right-handed hitters (and the same for lefties). Having this advantage against a lot of opposing hitters can have a huge impact on whether a pitcher will perform well or struggle on any given day.
• Mike Yastrzemski – Over/Under 0.5 Hits (-205/+155)
  Mike Yastrzemski is projected to bat 1st in the lineup in this game, which would be an upgrade from his 73% rate of hitting in the bottom-half of the lineup this year.
  Explain: The higher in the order a player bats, the more plate appearances he will get and the more opportunities he will get to hit the Over for every market. A player who hits higher in the order than he normally does may provide extra value opportunity since the market may be based on him hitting lower.
• San Francisco Giants – 2H Moneyline
  According to the leading projection system (THE BAT), the San Francisco Giants’ bullpen projects as the 2nd-best out of all teams in Major League Baseball.
  Explain: Most bettors only consider the starting pitcher, but a strong bullpen sneakily creates a tougher matchup for the opposing offense and suppresses a game’s runs.

Los Angeles Angels Insights

• Kyle Hendricks – Over/Under 3.5 Strikeouts (-135/+105)
  Kyle Hendricks’s 87.3-mph fastball velocity since the start of last season ranks in the 1st percentile among all SPs.
  Explain: Velocity is a key component to fastball success in generating strikeouts and preventing runs.
• Nolan Schanuel – Over/Under 0.5 Total Bases (-160/+125)
  The San Francisco Giants have just 1 same-handed RP in their bullpen, so Nolan Schanuel stands a good chance of never losing the platoon advantage against the ‘pen all game.
  Explain: Hitters perform worse against pitchers of the same handedness (i.e. righty-vs-righty), and being able to avoid those matchups against the bullpen boosts performance and creates hidden edge.
• Mike Trout – Over/Under 0.5 Total Bases (-150/+120)
  Mike Trout projects as the 11th-best batter in baseball, according to the leading projection system (THE BAT X).
  Explain: THE BAT X is a highly sophisticated projection system that accounts for a multitude of factors and regularly tests among the most accurate systems available.

Betting Trends

• Los Angeles Angels – 1st Five Innings (F5) Moneyline (+115)
  The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 6 of their last 18 games (+0.55 Units / 3% ROI)
• Heliot Ramos – Over/Under 0.5 RBIs (+165/-215)
  Heliot Ramos has hit the RBIs Under in his last 10 games (+10.00 Units / 41% ROI)