Cardinals vs Pirates Picks and Betting Odds - 4/28/2026

+140O/U: 8.5
(-110/-110)-160

Kyle Leahy – Over/Under 3.5 Strikeouts (-150/+115)
The Pittsburgh Pirates have 6 hitters in the projected offense that will have the benefit of the platoon advantage against Kyle Leahy in this matchup.
Explain: Right-handed pitchers perform worse against left-handed hitters (and visa-versa). If several hitters hold this advantage against the pitcher, it can have a huge impact on whether he will perform well or struggle on any given day.
Ivan Herrera – Over/Under 0.5 Hits (-225/+170)
The leading projection system (THE BAT X) projects Ivan Herrera in the 96th percentile when assessing his batting average skill.
Explain: THE BAT X is a highly sophisticated projection system that accounts for a multitude of factors and regularly tests among the most accurate systems available. Batting average is the most common measure of a player’s ability to generate hits.
Ivan Herrera – Over/Under 1.5 Total Bases (+140/-185)
When estimating his overall offensive skill, Ivan Herrera ranks in the 96th percentile according to the leading projections (THE BAT X).
Explain: THE BAT X is a highly sophisticated projection system that accounts for a multitude of factors and regularly tests among the most accurate systems available.

Oneil Cruz – Over/Under 1.5 Total Bases (+110/-140)
Oneil Cruz has strong power (98th percentile) if he makes contact, but that’s always far from assured (30.9% K%). Today, however, opposing pitcher Kyle Leahy has a pitch-to-contact profile (7th percentile K%) — great news for Cruz.
Explain: If he is less likely to strikeout, he’ll be more likely to make contact, which is often hard, home-run contact.

Pittsburgh Pirates – Run Line -1.5 (+135)
The Pittsburgh Pirates have hit the Run Line in 10 of their last 16 games at home (+5.85 Units / 31% ROI)
St. Louis Cardinals – Over/Under 3.5 Team Total (-120/-110)
The St. Louis Cardinals have hit the Team Total Over in 10 of their last 14 away games (+5.75 Units / 35% ROI)
JJ Wetherholt – Over/Under 0.5 Home Runs (+700/-1500)
JJ Wetherholt has hit the Home Runs Over in 3 of his last 4 games (+21.10 Units / 528% ROI)

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