Live Score for Cardinals vs Pirates - September 22nd, 2026

+140O/U: 7
(-110/-110)-165

Andre Pallante – Over/Under 3.5 Strikeouts (-160/+125)
Andre Pallante’s higher utilization percentage of his secondary pitches this season (49.2% vs. 42.8% last season) figures to work in his favor since they are typically much more effective than fastballs.
Explain: A pitcher who limits has fastball usage will instead heavily use change-ups, curveballs, sliders, etc. These are far more effective pitches at preventing runs and generating strikeouts.
Ivan Herrera – Over/Under 0.5 Total Bases (-180/+135)
In the past two weeks, Ivan Herrera’s Barrel% has experienced a negative regression, plummeting from his seasonal rate of 5.3% down to 0%.
Explain: Barrel% measures how often a player hits the ball at the optimal exit velocity and launch angle and is a terrific measure of underlying power.
St. Louis Cardinals – 2H Moneyline
According to the leading projection system (THE BAT), the St. Louis Cardinals’ bullpen ranks as the 10th-best out of all major league teams.
Explain: Most bettors only consider the starting pitcher, but a strong bullpen sneakily creates a tougher matchup for the opposing offense and suppresses a game’s runs.

Pittsburgh Pirates – Moneyline (-165)
The Pittsburgh Pirates outfield defense projects as the weakest among every team today.
Explain: Defense is an integral part of preventing (or, in this case, allowing) hits and runs.
Oneil Cruz – Over/Under 0.5 Total Bases (-180/+135)
Oneil Cruz’s average exit velocity has decreased this year; his 95.9-mph average last season has lowered to 93.7-mph.
Explain: Hitting the ball hard increases the chances of either a home run or the ball landing in fair territory for a hit before a fielder can get to it.
Spencer Horwitz – Over/Under 0.5 Total Bases (-155/+120)
Spencer Horwitz has an 86th percentile opposite-field rate on his flyballs (34.9%) and has the misfortune of hitting them towards baseball’s 10th-deepest LF fences in today’s matchup.
Explain: This player’s skill set does not match up particularly well with the park he’s in today, which may lead to worse-than-usual performance.

Pittsburgh Pirates – Run Line -1.5 (+135)
The Pittsburgh Pirates have hit the Run Line in 8 of their last 10 games (+6.55 Units / 45% ROI)
St. Louis Cardinals – 1st Five Innings (F5) Moneyline (+130)
The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 16 of their last 25 away games (+12.50 Units / 46% ROI)
Thomas Saggese – Over/Under 0.5 Singles (+120/-150)
Thomas Saggese has hit the Singles Over in 13 of his last 20 games (+7.25 Units / 33% ROI)

WriteNow™ by EV Analytics