See the Astros vs Angels Matchup Preview and Score Prediction – Saturday September 27th, 2025

Houston Astros

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Los Angeles Angels

On September 27, 2025, the Los Angeles Angels will host the Houston Astros at Angel Stadium in an American League West showdown. In their previous meeting, the Angels pulled off a close win, edging the Astros 4-3, which adds some intrigue to this matchup. The Angels, currently sitting at 72-88, are having a below-average season, while the Astros, boasting an 85-75 record, are performing above expectations.

Caden Dana is projected to take the mound for the Angels. Despite a rough year, with an 0-3 record and a troubling 6.39 ERA, Dana showed signs of improvement in his last start on September 21, where he allowed just 2 earned runs over 6 innings. His high walk rate may be mitigated by the Astros’ low-walk offense, which could give him a fighting chance. The projections suggest he may perform better than his numbers indicate, especially considering his xFIP of 4.82, hinting at some bad luck this season.

On the other side, A.J. Blubaugh is slated to pitch for the Astros. Although his ERA is an impressive 1.93, his 3.73 xFIP suggests he may not sustain this level of performance going forward. Blubaugh’s last outing on September 16 saw him pitch 3 innings with no earned runs, but he faces a challenge against a powerful Angels offense that ranks 4th in MLB with 225 home runs this season.

The Angels might be underdogs with a moneyline of +120, but their recent power surge offers them a glimmer of hope against a high-flyball pitcher like Blubaugh. With a game total set at 9.0 runs, bettors should keep an eye on both teams’ offensive capabilities as the Angels look to build off their recent success.

Houston Astros Insights

• Houston Astros – 1st Five Innings (F5) Moneyline (-155)
  In his previous game started, A.J. Blubaugh was on point and gave up 2 ER.
  Explain: A pitcher who was strong in his last outing may be sharp once again in his next outing.
• Jesus Sanchez – Over/Under 0.5 Total Bases (-150/+115)
  Based on Statcast data, the leading projection system (THE BAT X)’s version of Expected HR per 600 plate appearances (24.1) implies that Jesus Sanchez has suffered from bad luck this year with his 16.0 actual HR/600.
  Explain: xHR uses highly advanced Statcast data to measure a player’s home run ability more accurately than actual home runs can.
• Houston Astros – 2H Moneyline
  The Houston Astros bullpen profiles as the 5th-worst in MLB, via the leading projection system (THE BAT).
  Explain: Most bettors only consider the starting pitcher, but a weak bullpen sneakily creates an easier matchup for the opposing offense and boosts a game’s runs.

Los Angeles Angels Insights

• Caden Dana – Over/Under 15.5 Pitching Outs (+140/-180)
  Tallying 12.7 outs per game per started since the start of last season on average, Caden Dana ranks in the 18th percentile.
  Explain: A pitcher who averages more outs per start than his Outs prop may be a good bet to go over, and visa-versa for the under.
• Jo Adell – Over/Under 0.5 Hits (-205/+155)
  Jo Adell is penciled in 4th on the lineup card in this matchup, which would be an upgrade from his 54% rate of hitting in the bottom-half of the lineup this season.
  Explain: The higher in the order a player bats, the more plate appearances he will get and the more opportunities he will get to hit the Over for every market. A player who hits higher in the order than he normally does may provide extra value opportunity since the market may be based on him hitting lower.
• Bryce Teodosio – Over/Under 0.5 Total Bases (-115/-115)
  The leading projection system (THE BAT X) projects Bryce Teodosio in the 3rd percentile when assessing his overall offensive talent.
  Explain: THE BAT X is a highly sophisticated projection system that accounts for a multitude of factors and regularly tests among the most accurate systems available.

Betting Trends

• Los Angeles Angels – Over/Under 3.5 Team Total (-140/+110)
  The Los Angeles Angels have hit the Team Total Under in 34 of their last 51 games (+15.90 Units / 26% ROI)
• Houston Astros – Over/Under 4.5 Team Total (-130/+100)
  The Houston Astros have hit the Team Total Under in 85 of their last 147 games (+15.00 Units / 9% ROI)
• Carlos Correa – Over/Under 0.5 Singles (-125/-105)
  Carlos Correa has hit the Singles Over in 18 of his last 25 away games (+9.30 Units / 29% ROI)