Official Lineup for Cardinals vs Orioles – 5/27/2025

St. Louis Cardinals

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Baltimore Orioles

As the Baltimore Orioles host the St. Louis Cardinals at Oriole Park at Camden Yards on May 27, 2025, both teams are looking to build momentum. The Orioles recently snapped a six-game losing streak with a 5-2 victory over the Cardinals in their previous matchup, while St. Louis is hoping to bounce back after the defeat.

The Orioles currently hold a disappointing 19-34 record, ranking 25th in the league, while the Cardinals sit at a respectable 30-24, ranking 17th. Despite their struggles, Baltimore’s offense ranks 10th in home runs, showcasing some power potential that could exploit the Cardinals’ weaker bullpen, which is ranked 23rd in MLB.

On the mound, Tomoyuki Sugano is set to start for the Orioles. Although he has a solid ERA of 3.07 this season, his underlying metrics indicate he may have been a bit lucky, as his xFIP stands at 4.44. Sugano’s low strikeout rate of 13.8% could be a concern, especially against a Cardinals lineup that is not particularly prone to striking out. The projections suggest he may struggle to find success against an average offense like St. Louis.

Andre Pallante, the Cardinals’ starter, comes in with an ERA of 4.18, which is above average. He also has a low strikeout rate of 14.8%, which may play into the Orioles’ favor. However, with the Orioles ranking 6th in strikeouts, Pallante might find himself in a position to capitalize on their weaknesses.

Betting markets have set the Orioles’ moneyline at +110, suggesting that oddsmakers expect a closely contested game. With both teams looking to establish a rhythm, this matchup could be pivotal for their respective seasons.

St. Louis Cardinals Insights

• St. Louis Cardinals – 2H Moneyline
  The St. Louis Cardinals bullpen profiles as the 8th-worst in the majors, per the leading projection system (THE BAT).
  Explain: Most bettors only consider the starting pitcher, but a weak bullpen sneakily creates an easier matchup for the opposing offense and boosts a game’s runs.

Betting Trends

• Baltimore Orioles – Over/Under 3.5 Team Total (-140/+110)
  The Baltimore Orioles have hit the Team Total Under in 27 of their last 42 games (+9.50 Units / 19% ROI)
• St. Louis Cardinals – Moneyline (-125)
  The St. Louis Cardinals have hit the Moneyline in 15 of their last 20 games (+10.75 Units / 47% ROI)