Betting Odds and Bets for D-Backs vs Giants – 9/10/25

Arizona Diamondbacks logo

Arizona Diamondbacks

@
San Francisco Giants logo

San Francisco Giants

+110O/U: 8.5
(-120/+100)
-130

As the San Francisco Giants prepare to host the Arizona Diamondbacks at Oracle Park on September 10, 2025, both teams find themselves in the thick of an intense series. The Giants narrowly topped the Diamondbacks 5-3 in their last encounter, setting the stage for what promises to be another competitive matchup.

In the current standings, the Giants hold a record of 74-71, while the Diamondbacks sit slightly behind at 72-74. Both teams are experiencing average seasons, but the Giants have a slight edge in overall performance. According to the leading MLB projection system, Carson Seymour is projected to take the mound for the Giants. Although he has struggled at times, recently showing a mixed bag of results with a 1-2 record and a 4.25 ERA, his last outing on September 5 was promising, allowing just 1 earned run over 5 innings.

On the other side, Eduardo Rodriguez, despite being a below-average pitcher with a 5.22 ERA, showcased potential in his last start, tossing 6 innings with only 1 earned run allowed. This game features two pitchers who have faced challenges this season, making it a battle of who can limit damage and exploit the opponent’s weaknesses.

The Diamondbacks possess a powerful offense, ranking 6th best in MLB with 198 home runs this season, while the Giants have struggled offensively, ranking 18th overall. The Giants’ ability to harness their pitching depth, especially with a high-groundball pitcher like Seymour, might give them an advantage against the Diamondbacks’ potent lineup.

Betting markets see this as a close contest, with the Giants slightly favored. The current moneyline places the Giants at -130, indicating an implied team total of 4.45 runs, while the Diamondbacks sit at +110 with an average implied total of 4.05 runs. If the Giants can capitalize on their home-field advantage and strong pitching, they may very well secure another victory in this crucial series.

Arizona Diamondbacks Insights

  • Arizona Diamondbacks – Moneyline (+110)
    The Arizona Diamondbacks outfield defense projects as the best among all the teams in action today.
    Explain: Defense is an integral part of preventing hits and runs.
  • Jake McCarthy – Over/Under 0.5 Total Bases (-175/+135)
    Typically, bats like Jake McCarthy who hit a lot of flyballs generally hit worse when facing pitchers who also induce a lot of flyballs such as Carson Seymour.
    Explain: This mostly has to do with the way the hitter’s swing plane interacts with the pitch trajectory, and it can create diminished performance across all categories and hidden value few are considering.
  • Arizona Diamondbacks bats collectively grade out 10th- in MLB for power this year when judging by their 9.2% Barrel%.
    Explain: Barrel% measures how often a player hits the ball at the optimal exit velocity and launch angle and is a terrific measure of underlying power.

San Francisco Giants Insights

  • Carson Seymour – Over/Under 3.5 Strikeouts (-140/+110)
    Because groundball hitters face a disadvantage against groundball pitchers, Carson Seymour (48.6% GB% according to the leading projection system, THE BAT) is well-situated in today’s game with 3 GB hitters in the opposing team’s projected lineup.
    Explain: This mostly has to do with the way the hitter’s swing plane interacts with the pitch trajectory, and it can create boosted performance across all categories and hidden value few are considering.
  • Jung Hoo Lee – Over/Under 0.5 Hits (-160/+125)
    Jung Hoo Lee is projected to hit 7th in the batting order in this game, which would be a downgrade from his 66% rate of hitting in the top-half of the batting order this season.
    Explain: The lower in the order a player bats, the fewer plate appearances he will get and the fewer opportunities he will get to hit the Over for every market. A player who hits lower in the order than he normally does may provide extra value opportunity since the market may be based on him hitting higher.
  • Heliot Ramos – Over/Under 1.5 Total Bases (+120/-155)
    Heliot Ramos has an 89th percentile opposite-field rate on his flyballs (36%) and is a great match for the park considering he’ll be hitting them out towards the game’s 2nd-shallowest RF fences in today’s game.
    Explain: This player’s skill set matches up particularly well with the park he’s in today, which may lead to better-than-usual performance.

Betting Trends

  • San Francisco Giants – Over/Under 4.5 Team Total (+105/-135)
    The San Francisco Giants have hit the Team Total Over in 17 of their last 22 games (+11.60 Units / 46% ROI)
  • Arizona Diamondbacks – 1st Five Innings (F5) Moneyline (-110)
    The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 56 of their last 103 games (+14.95 Units / 10% ROI)
  • Rafael Devers – Over/Under 0.5 Walks (+165/-215)
    Rafael Devers has hit the Walks Over in 14 of his last 20 games (+12.65 Units / 61% ROI)